I concur with Jedi on the beer places. I really enjoyed Mantra with Tara, Gilly, and Donny. When Brac and I went to Bearded Iris we happened into some kind of spoken word open mike night, the beer was good but it was an odd experience. I've not been to Southern Grist, but I have really enjoyed their beers that I've had. Craft Brewed is a good bottle shop that serves by the drink if you want a variety of local and regional breweries. Yazoo is always good and it is only a couple of blocks from Jackalope for a 2 for 1 stop.
Here is a pretty good list (and a really crappy map) of most of the breweries in town.
Power just went out in my office, when I have a few more minutes, I'll talk about food.
ETA: Food
We don't get out a lot to eat and the kids a not very adventurous eaters so I don't know much about the food scene here. If you are interested in the hot chicken thing, I can help a little there. Hattie B's is not the best, but it is good and probably the most convenient with a couple of locations, reasonable eat-in space, and a handful of local beers available. Party Fowl is located between Yazoo and Jackalope and offers more of a dine in experience with a much more varied menu and a decent take on Nashville Hot Chicken. Outside the hot chicken stuff, i know that there are a bunch of new restaurants, I'm just not that familiar. If you have a particular interest, I can probably find out.
Let me know if you come in town, I'd like to have a couple of beers with you.